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目的探讨急性脑梗死与高敏反应蛋白水平及动脉斑块性质关系。方法 2007年1月至2010年3月收治的急性脑梗死患者146例(急性脑梗死组),选取同期进行健康体检人员150例(对照组),进行高敏C反应蛋白检测、血脂检测、颈动脉彩色多普勒检查并进行比较。结果经统计学分析,两组生化检测比CRP比较P<0.05有统计学意义。血脂项目比较P>0.05无显著差异性。斑块性质及发生率比较P<0.05有显著差异性。结论高敏反应蛋白不仅仅是一种炎症标记物,可以反应颈动脉内膜斑块的性质及稳定性,是不稳定性动脉粥样硬化疾病发生的危险信号,是脑梗死的致病因子。对急性脑梗死患者应加强对高敏反应蛋白检测,可以指导临床治疗防止脑梗死发生。
Objective To investigate the relationship between acute cerebral infarction and hypersensitivity protein and plaque characteristics. Methods From January 2007 to March 2010, 146 patients with acute cerebral infarction (acute cerebral infarction group) were enrolled and 150 healthy control subjects (control group) were selected during the same period. High-sensitivity C-reactive protein, lipids, carotid artery Color Doppler examination and comparison. Results By statistical analysis, two groups of biochemical tests compared with CRP P <0.05 was statistically significant. Blood lipids compared P> 0.05 no significant difference. Patch nature and incidence of P <0.05 significant difference. Conclusion Hypersensitive protein is not only an inflammatory marker, it can reflect the nature and stability of carotid artery plaque. It is a dangerous signal of unstable atherosclerotic disease and a causative factor of cerebral infarction. Patients with acute cerebral infarction should strengthen the detection of hypersensitivity protein can guide clinical treatment to prevent the occurrence of cerebral infarction.