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目的研究老年肾病综合征的临床诊断及治疗效果。方法 100例老年肾病综合征患者,随机分为观察组和对照组,各50例,对照组患者进行单纯的甲泼尼龙治疗,观察组患者在对照组基础上联合雷公藤多甙治疗,对比观察两组患者的临床治疗效果及不良反应。结果观察组患者的总有效率为94.0%,对照组患者的总有效率为82.0%,观察组明显高于对照组,差异具有统计学意义(P<0.05);在不良反应方面,观察组患者的发生率为8.0%,对照组患者为18.0%,观察组明显低于对照组,差异具有统计学意义(P<0.05)。结论对于老年肾病综合征患者采用甲泼尼龙联合雷公藤多甙治疗不仅可以显著提高临床治疗效果,而且还能降低并发症的发生率,值得临床推广使用。
Objective To study the clinical diagnosis and treatment of senile nephrotic syndrome. Methods 100 cases of elderly patients with nephrotic syndrome were randomly divided into observation group and control group, 50 cases in each group. Patients in control group were treated with methylprednisolone alone. Patients in observation group were treated with tripterygium glycosides on the basis of control group. Two groups of patients with clinical effects and adverse reactions. Results The total effective rate was 94.0% in the observation group and 82.0% in the control group. The observation group was significantly higher than the control group (P <0.05). In adverse reactions, the observation group In the control group was 8.0%, while that in the control group was 18.0%. The observation group was significantly lower than the control group, the difference was statistically significant (P <0.05). Conclusion The treatment of elderly patients with nephrotic syndrome using methylprednisolone combined with tripterygium wilfordii not only can significantly improve the clinical efficacy, but also reduce the incidence of complications, it is worth promoting the use of the clinic.