阿迪森氏病即原发性慢性肾上腺皮质功能不全,为各种原因引起肾上腺组织破坏,体内皮质醇类皮质激素缺乏所致,可同时有醛固酮类皮质激素缺乏。阿迪森氏病为罕见疾病,大多数为20～50岁成年人。小儿发病率各家报道不一,在美国和瑞士,约占儿科患者总数0.014%;在苏联,约占儿科内分泌患者数1%;在英国,则占儿科内分泌患者数0.5%或更少。一般认为年长儿发病多于年幼儿和婴儿,有病例分析称10～15岁小儿占95%,10岁以下小儿占5%,但也有相反结论的报道。 Addison’s disease is the primary chronic adrenal insufficiency, caused by various causes of adrenal tissue damage caused by the lack of cortisol in the body, but also the lack of aldosterone-like corticosteroids. Addison’s disease is a rare disease, most adults 20 to 50 years old. Pediatric morbidity rates vary from country to country, accounting for about 0.014% of all pediatric patients in the United States and Switzerland, 1% of pediatric endocrine patients in the Soviet Union, and 0.5% or less of pediatric endocrine patients in the United Kingdom. It is generally believed that the incidence of older children than young children and infants, a case analysis said 95% of children aged 10 to 15, 5% of children under 10 years old, but there are also reports of the opposite conclusion.