自从1827年Cumin首先报道铬化合物对接触者有害以来至今已有160多年历史了。关于铬及其化合物对接触者的毒作用研究正日趋深入。作者根据美国工业卫生基金会、美国环境保护局等研究机构近年来铬化合物毒作用研究的文献资料,阐述了铬化合物的肾脏毒作用、致畸、致癌效应以及接触者生物学监测等方面的研究进展。 It has been more than 160 years since Cumin first reported in 1827 that chromium compounds were harmful to their contacts. Research on the toxic effects of chromium and its compounds on contacts is deepening. According to the literature of toxicological studies of chromium compounds in recent years by the U.S. Industrial Health Foundation, the U.S. Environmental Protection Agency and other research institutes, the authors describe the studies on the renal toxicity, teratogenicity, carcinogenic effects and biological monitoring of contact in chrome compounds progress.