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目的探讨胃镜下氩气刀治疗食管上皮内瘤变(IEN)的临床疗效。方法选择45例食管上皮内瘤变患者进行胃镜下氩气刀(APC)治疗,术后1、3、6、12个月进行临床随访及胃镜复查,评价其疗效。结果 45例患者均能一次性给予病灶灼除,术后出现胸骨后疼痛27例,9例出现恶心、返酸症状,给予抑酸治疗后均好转,无一例出现出血、穿孔。所有患者均按时随访,未见复发。结论氩气刀可用于治疗食管上皮内瘤变。
Objective To investigate the clinical efficacy of argon gas knife under endoscopy in the treatment of esophageal intraepithelial neoplasia (IEN). Methods Forty-five patients with esophageal intraepithelial neoplasia were treated with gastroscopic argon knife (APC). The patients were followed up and gastroscopy at 1, 3, 6, and 12 months after operation to evaluate the curative effect. Results All the 45 patients were given a one-time focal burns. There were 27 cases of post-sternal pain and 9 cases of nausea and acid reflux symptoms. All patients were ameliorated after acid suppression. No bleeding or perforation occurred. All patients were followed up on time, no recurrence. Conclusion argon knife can be used to treat esophageal intraepithelial neoplasia.