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目的:探讨血浆循环DNA与肺癌复发转移患者的相关性。方法:提取血浆循环DNA并进行定量检测,统计学分析各组之间血浆循环DNA的差异。结果:肺癌患者血浆循环DNA显著高于正常对照组;肺癌复发转移患者在复发转移前、后血浆循环DNA含量均显著升高,且差异有显著性。结论:血浆循环DNA有可能作为肺癌复发转移的一种检测指标。
Objective: To investigate the correlation between plasma circulating DNA and recurrence and metastasis of lung cancer. Methods: Plasma circulating DNA was extracted and quantified. Statistical analysis was made of the differences in plasma circulating DNA between the groups. Results: The plasma circulating DNA of patients with lung cancer was significantly higher than that of the normal control group; the circulating DNA content of the patients with recurrence and metastasis of lung cancer before and after recurrence and metastasis were significantly increased, and the difference was significant. Conclusion: Plasma circulating DNA may be used as a detection index for the recurrence and metastasis of lung cancer.