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对慢性丙型肝炎(CHC)患者临床资料进行总结分析,并用逆转录套式聚合酶链反应(PCR)检测血清中丙型肝炎病毒核糖核酸(HCV—RNA)。结果:①本地区CHC患者黄疸发生率为28％,②60％CHC患者血清中可检出HCV—RNA,⑧黄疸组病人HCV—RNA检出率(85.7％)明显高于无黄疸组病人(50％)(P<0.05),④不同范围血清丙氨酸氨基转移酶(ALT)内HCV—RNA检出率不等。
The clinical data of patients with chronic hepatitis C (CHC) were analyzed. The serum hepatitis C virus RNA (HCV-RNA) was detected by reverse transcription polymerase chain reaction (PCR). Results: ① The incidence of jaundice in CHC patients in this area was 28%. ② HCV-RNA was detected in serum of 60% CHC patients. ⑧ The detection rate of HCV-RNA in patients with jaundice (85.7%) was significantly higher than that of patients without jaundice %) (P <0.05). ④ The detection rates of HCV-RNA in different ranges of serum alanine aminotransferase (ALT) were different.