目的探讨应用乙酰甲胆碱激发试验早期诊断支气管哮喘的价值。方法采用德国Jaeger公司产的复合式肺功能仪进行乙酰甲胆碱吸入激发试验。结果支气管激发试验阳性且基础肺功能指标正常的患者,小气道功能指标已有改变。结论对于有可疑哮喘病史者,气道反应性测定可作为排除或确定诊断的有力依据。 Objective To investigate the value of early diagnosis of bronchial asthma by methacholine stimulation test. Methods Methacholine inhalation challenge test was performed with the compound lung functionometer manufactured by Jaeger Company in Germany. Results In patients with positive bronchial provocation test and normal baseline pulmonary function, small airway function indices have been changed. Conclusions For those with a history of suspicious asthma, the airway reactivity assay can be used as a strong basis for excluding or confirming a diagnosis.