交感神经过度激活是高血压尤其是难治性高血压(resistant hypertension,RH)发生和维持的重要机制[1]。多项研究表明以肾交感神经为靶点的经皮经导管射频消融去肾交感神经术(renal denervation,RDN)能安全有效地降压[2-7]。然而现今的螺旋式消融却有一定盲目性,因导管可能在交感神经并不密集的区域无效消融,这也可能是术后无降压反应(术后半 Sympathetic overactivity is an important mechanism of occurrence and maintenance of hypertension, especially refractory hypertension (RH) [1]. Several studies have demonstrated that percutaneous transcatheter radiofrequency ablation of renal denervation (RDN) targeting the renal sympathetic nerve can safely and effectively depressurize [2-7]. However, today’s helical ablation is somewhat blind because catheters may be ineffective in areas of lessened sympathetic ablation, which may also be postoperative non-hypotensive (postoperative half