1临床资料患者,女,54岁,农民,因“心慌、胸闷27年,加重伴反复全身浮肿7年”入院。患者27年前开始出现心慌、胸闷,因症状不重能够坚持一般的体力劳动,从未进行正规诊治。7年前症状逐渐加重并反复出现全身浮肿,并以双下肢明显,曾在多家医院就诊,均诊断为“风湿性心脏病联合瓣膜病 1 Clinical data Patient, female, 54 years old, farmer, because of “palpitation, chest tightness, 27 years, aggravating with repeated systemic edema for 7 years” admission. 27 years ago, patients began to appear palpitation, chest tightness, not due to symptoms can adhere to the general manual labor, has never been formal diagnosis and treatment. 7 years ago, the symptoms gradually aggravated and repeated systemic edema, and obvious lower extremities, had seen in many hospitals, were diagnosed as "rheumatic heart disease associated with valvular disease