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目的 :探讨脑脊液 C反应蛋白 (CRP)、铜蓝蛋白 (CP)的水平变化对颅内感染疾病的诊断价值。方法 :采用Array36 0型特定蛋白分析仪测定患者脑脊液 (CSF)中 CRP、CP的含量。结果 :化脓性脑膜炎、结核性脑膜炎患者 CSF中CRP含量较正常对照组明显升高 (P<0 .0 1)。化脓性脑膜炎患者 CSF中 CP含量较正常对照组明显升高 (P<0 .0 1)。结论 :CSF中 CRP、 CP联合检测对颅内感染性疾病的诊断、鉴别诊断有重要意义。
Objective: To investigate the diagnostic value of cerebrospinal fluid levels of C-reactive protein (CRP) and ceruloplasmin (CP) in the diagnosis of intracranial infection. Methods: The content of CRP and CP in cerebrospinal fluid (CSF) of patients was determined by Array36 0 specific protein analyzer. Results: The CRP level in CSF of patients with purulent meningitis and tuberculous meningitis was significantly higher than that of the control group (P <0.01). The content of CP in CSF of patients with purulent meningitis was significantly higher than that of normal control group (P <0.01). Conclusion: The combined detection of CRP and CP in CSF is of great significance in the diagnosis and differential diagnosis of intracranial infectious diseases.