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C反应蛋白(C-reactive protein,CRP)是一种非特异性的急性炎症时相反应蛋白。冠心病本质上是一种慢性炎性增生性疾病,作为炎症标志物的CRP血清水平的升高已被公认为是心血管疾病事件的强有力的独立危险因素或预测因素。牙周炎患者血清CRP水平亦显著升高。本文就CRP在牙周炎和冠心病相互影响中的作用进行综述。
C-reactive protein (CRP) is a nonspecific acute inflammatory phase reaction protein. Coronary heart disease is essentially a chronic inflammatory proliferative disease and the elevation of CRP serum levels as markers of inflammation has been recognized as a potent, independent risk factor or predictor of cardiovascular disease events. Patients with periodontitis serum CRP levels also significantly increased. This article reviews the role of CRP in the interaction between periodontitis and coronary heart disease.