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目的:不孕不育女性患者生殖道支原体感染及耐药情况分析。方法:回顾分析义乌市妇幼保健院妇科门诊收治的132例不孕不育女性患者的临床资料,并选择68例同期早孕健康妇女为对照组,对入选患者的支原体感染及耐药情况进行分析。结果:观察组患者支原体感染阳性率显著高于对照组患者支原体感染阳性率,差异有统计学意义(P值<0.05)。观察组患者单纯解脲支原体感染率、单纯人型支原体感染率和解脲支原体和人型支原体混合感染率均显著高于对照组患者相应的感染率,差异有统计学意义(P值<0.05)。观察组患者感染支原体对美满霉素、交沙霉素、米诺环素和多西环素耐药性低,对克拉霉素、罗红霉素、阿奇霉素、诺氟沙星、氧氟沙星和左氧氟沙星耐药性高。结论:不孕不育女性患者支原体感染的主要病毒为解脲支原体,其中检出的支原体对美满霉素、米诺环素和多西环素高度敏感,可作为患者治疗的首选药物。
Objective: Infection and drug resistance of mycoplasma in genital tract in infertile women. Methods: The clinical data of 132 cases of infertile women admitted to gynecology outpatient department of Yiwu MCH hospital were retrospectively analyzed, and 68 healthy pregnant women of the same period as the control group were selected as the control group. Mycoplasma infection and drug resistance of the selected patients were analyzed. Results: The positive rate of mycoplasma infection in observation group was significantly higher than that in control group, the difference was statistically significant (P <0.05). The infection rates of Ureaplasma urealyticum, Mycoplasma hominis and Mycoplasma hominis in the observation group were all significantly higher than those in the control group, with significant difference (P <0.05). Mycoplasma infection in the observation group patients with low resistance to minocycline, josamycin, minocycline and doxycycline, clarithromycin, roxithromycin, azithromycin, norfloxacin, ofloxacin And levofloxacin high drug resistance. Conclusion: The main virulent mycoplasma infection in infertile women is Ureaplasma urealyticum. Mycoplasma detected is highly sensitive to minocycline, minocycline and doxycycline, and can be used as the drug of choice for patients.