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细胞因子的生物学功能主要是通过“ＪＡＫｓ -ＳＴＡＴｓ”或“Ｒａｓ-ＭＡＰＫ”信号传导途径实现。自从在干扰素对培养细胞基因转录诱导研究中发现ＪＡＫｓ -ＳＴＡＴｓ细胞因子信号传导途径以来 ,它一致成为当前细胞因子研究领域的热点。细胞因子受体信号传导的ＪＡＫｓ -Ｓ
The biological function of cytokines is mainly through the “JAKs-STATs” or “Ras-MAPK” signaling pathways. Since the discovery of the JAKs-STATs cytokine signaling pathway in interferon-induced gene transcriptional induction in cultured cells, it has consistently become a hot spot in the field of cytokine research. Cytokine receptor-mediated JAKs -S