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目的 探讨肾素 -血管紧张素系统 (RAS)在肾脏病中的作用及阻断RAS后对肾脏病的影响。方法 总结并分析近 1 0年相关文献。结果 血管紧张素Ⅱ在肾小球硬化中起重要作用 ,血管紧张素转化酶抑制剂 (ACEI)和血管紧张素Ⅱ受体 1拮抗剂 (AT1 RA)对肾脏有相同的保护作用。结论 ACEI和AT1 RA可阻断RAS对肾脏的损害
Objective To investigate the role of renin-angiotensin system (RAS) in renal disease and the effect of RAS on renal disease. Methods Summarize and analyze the related literatures in recent 10 years. Results Angiotensin Ⅱ plays an important role in glomerulosclerosis. Angiotensin-converting enzyme inhibitor (ACEI) and angiotensin Ⅱ receptor 1 antagonist (AT1 RA) have the same protective effect on kidneys. Conclusion ACEI and AT1 RA can block the renal damage caused by RAS