据老年大鼠在Morris水迷宫中的行为表现,将其分为老年学习记忆减退和学习记忆正常两部分.采用透射电镜观察、拍片,对齿状回中分子层突触的数量和大小进行体视学定量分析.结果表明:老年记忆减退鼠突触数密度、面密度较老年正常和青年鼠明显减少.单个突触平均面积较其显著增大,且与大鼠行为显著相关. According to the behavior of senile rats in the Morris water maze, we divided them into senile learning and memory loss and normal learning and memory two parts.Using transmission electron microscope observation, filming, the number and size of synapses in the dentate gyrus Quantitative analysis of visual acuity showed that the synaptic density and facial density of senile memory deficit rats were significantly lower than those of normal aged and young rats, and the average area of ​​single synapse was significantly increased compared with that of aged rats.