B细胞增生因子(BCGF)和B细胞分化因子(BCDF)是最近新认识的两种因子,它们分别对B细胞增生和分化起诱导作用.本文将对这两种因子的来源、理化特性、以及它们在B细胞活化周期中的作用和受体表达做一扼要介绍.一、B细胞增生因子(BCGF)(1)促有丝分裂素诱导T细胞产生的BCGF:在T-T杂交瘤产生之前,人类的BCGF主要是从PHA、PWM和ConA刺激 B cell proliferative factor (BCGF) and B cell differentiation factor (BCDF) are two newly recognized factors, which induce the proliferation and differentiation of B cells respectively.This paper will analyze the origin, physicochemical properties, Their role in B-cell activation cycle and receptor expression make a brief introduction .B cell proliferative factor (BCGF) (1) mitogenicinducible T cell-induced BCGF: Before the generation of TT hybridoma, human BCGF Primarily stimulated by PHA, PWM and ConA