All motions provide sensory, motoric, and reflexive input to the central nervous system, as well as playing animportant role in cerebral functional plasticity and compensation. Cerebral plasticity has become thetheoretical basis of neurorehabilitation. Studies of cerebrovascular disease, in particular, demonstrate thatregeneration is accompanied by multiple forms of plasticity, such as functional and structural, in differentphases of stroke rehabilitation. This study was designed to measure synaptic plasticity and expression ofassociated proteins to analyze the effect of rehabilitation training on learning and memory in a rat model ofcerebral infarction. Results suggest that rehabilitation training increases expression of nerve growth factorassociated protein 43, brain-derived neurotrophic factor, and neural cell adhesion molecules, and alsopromotes cerebral functional plasticity. All motions provide sensory, motoric, and reflexive input to the central nervous system, as well as playing animportant role in cerebral functional plasticity and compensation. Cerebral plasticity has become thetheoretical basis of neurorehabilitation. In particular, demonstrate thatregeneration is accompanied by multiple forms of plasticity, such as functional and structural, in differentphases of stroke rehabilitation. This study was designed to measure synaptic plasticity and expression ofassociated proteins to analyze the effect of rehabilitation training on learning and memory in a rat model of cerebral infarction. Results suggest that rehabilitation training increases expression of nerve growth factorassociated protein 43, brain-derived neurotrophic factor, and neural cell adhesion molecules, and alsopromotes cerebral functional plasticity.