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观察了28例冠心病心绞痛患者采用生脉注射液治疗前后血液流变学、运动耐量及其心电图的变化。结果表明,生脉注射液可显著降低血液粘度指标(P<0.05),增加运动量及运动时间,提高最大心率血压双乘积并可减少运动心电图总ST段下移幅值(P<0.05及P<0.01)。提示生脉注射液可通过降低血液粘度等作用提高心绞痛患者心脏功能,并减轻运动负荷下心肌缺血程度。
The changes of hemorheology, exercise tolerance and ECG before and after treatment with Shengmai injection were observed in 28 patients with coronary heart disease and angina pectoris. The results showed that Shengmai injection can significantly reduce the blood viscosity index (P <0.05), increase the amount of exercise and exercise time, increase the maximum heart rate and blood pressure double product and reduce the total amplitude of the motion of the total ST segment of the electrocardiogram (P <0. 05 and P<0.01). It is suggested that Shengmai injection can improve cardiac function of patients with angina pectoris by reducing the viscosity of blood, and reduce the degree of myocardial ischemia under exercise load.