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目的研究蓬莱市发热伴血小板减少综合征死亡病例的临床特点,提高对危重患者的识别能力。方法对蓬莱市人民医院2011—2013年收治的14例发热伴血小板减少综合征死亡病例进行回顾性临床分析。结果所有患者均有发热(100.00%),主要症状是乏力、全身酸痛、纳差和恶心,主要体征为腹股沟淋巴结肿大和触痛(78.57%),舌体及肢体震颤(92.86%)。发病早期出现外周血白细胞降低(92.86%)、血小板降低(100.00%),蛋白尿,100%患者ALT、AST、LDH、CKMB升高,50%患者合并基础疾病。平均死亡年龄68.13岁,发病至死亡平均时间10.36 d。结论既往有基础疾病和有神经系统症状的患者,死亡率高。
Objective To study the clinical features of deaths caused by fever with thrombocytopenia in Penglai City and to improve the ability of patients with critical illness. Methods Retrospective clinical analysis of 14 deaths from patients with fever and thrombocytopenia admitted in Penglai People’s Hospital from 2011 to 2013 was retrospectively analyzed. Results All patients had fever (100.00%). The main symptoms were fatigue, general aches, anorexia and nausea. The main symptoms were enlarged inguinal lymph nodes and tenderness (78.57%) and tremorment of the tongue and limb (92.86%). Early onset of peripheral leukopenia (92.86%), thrombocytopenia (100.00%), proteinuria, 100% of patients with ALT, AST, LDH, CKMB increased, 50% of patients with underlying diseases. The average age of death was 68.13 years old, the average time to death was 10.36 days. Conclusion Patients with previous underlying diseases and neurological symptoms have a high mortality rate.