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血管肉瘤(angiosarcoma,As)是起源于血管或淋巴管内皮细胞的高度恶性软组织肿瘤~([1]),占软组织肉瘤的2%。肿瘤由不同程度异型性的内皮细胞构成,可表现为从分化很好而类似良性血管瘤到分化很差而呈实性巢状,与癌、黑色素瘤及其他类型的肉瘤难以区别。原因不明,可能与癌症、损伤、慢性炎症、体内异物等有关。1临床资料患者,男,49岁,2014年6月因“胸骨柄处触及结节(约0.3 cm×0.5 cm),伴阵发性刺样痛、乏力”当地医院就诊,行
Angiosarcoma (As) is a highly malignant soft tissue tumor that originates from vascular or lymphatic endothelial cells (1), accounting for 2% of soft tissue sarcomas. Tumors are composed of endothelial cells of varying degree and atypia, which can be characterized as well-differentiated neoplasms with well-differentiated and benign hemangiomas, which are indistinguishable from carcinomas, melanomas and other types of sarcomas. For unknown reasons, may be related to cancer, injury, chronic inflammation, foreign body and so on. A clinical data of patients, male, 49 years old, in June 2014 because of “nodules touched the sternum (about 0.3 cm × 0.5 cm), with paroxysmal thorn pain, fatigue,” the local hospital, line