论文部分内容阅读
目的检测老年代谢综合症患者的白介素-6(IL-6),DD聚体,抗凝血酶Ⅲ,纤维蛋白原的表达水平,评价IL-6在老年MS线血栓性疾患中的诊断意义。方法以28例老年代谢综合症患者为研究对象,根据超声、CT血管造影(CTA)、磁共振血管造影(MRA)、血管造影等检查将其分为A组(对照组)和B组(血栓组),分别测定两组患者血清IL-6,DD聚体,抗凝血酶Ⅲ,纤维蛋白原水平。结果 B组(血栓组)血清中IL-6,DD聚体,抗凝血酶Ⅲ,纤维蛋白原水平均明显高于A组(对照组),IL-6与DD聚体,抗凝血酶Ⅲ,纤维蛋白原有明显相关性(P<0.01)。结论在老年代谢综合症患者中,IL-6与DD聚体,抗凝血酶Ⅲ,纤维蛋白原等血栓检测指标有一定的相关性,表达水平对辅助诊断血栓性疾患有一定的临床价值和指导意义。
Objective To detect the expression of interleukin-6 (IL-6), DD-polymer, antithrombin Ⅲ and fibrinogen in elderly patients with metabolic syndrome and to evaluate the diagnostic value of IL-6 in the diagnosis of thrombotic disorders in the elderly MS line. Methods Twenty-eight elderly patients with metabolic syndrome were enrolled in this study. Patients were divided into group A (control group) and group B (group C) according to ultrasound, CT angiography (CTA), magnetic resonance angiography (MRA) Group). Serum levels of IL-6, DD-dimer, antithrombin Ⅲ and fibrinogen were measured in two groups. Results The serum levels of IL-6, DD, antithrombin Ⅲ and fibrinogen in group B (thrombosis group) were significantly higher than those in group A (control group), IL-6 and DD aggregates, antithrombin Ⅲ , Fibrinogen had significant correlation (P <0.01). Conclusion In the elderly patients with metabolic syndrome, IL-6 and DD polymer, antithrombin Ⅲ, fibrinogen and other indicators of thrombosis have a certain correlation, the expression level of the diagnosis of thrombotic disorders have some clinical value and Guiding significance.