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虽然鼠疫活菌苗的免疫效果是公认的,但最近出于化学疫苗的创立,在完善鼠疫予防接种问题上具有极大的意义。对有关鼠疫菌抗原保护性的试验资料分析表明,首先是F_1和菌体细胞表面的生物聚合物表现有较大免疫原性成分。实验证明,它们对多种实验动物均有保护力。对其他鼠疫菌抗原制剂(ОСА,ЛПС,V,T,L,4等)的保护性研究得不够充分。但也有少数材料,可以设想在预防鼠疫免疫中至少其中某些抗原带来
Although the immunization efficacy of live vaccine against plague is generally acknowledged, the recent establishment of a chemical vaccine has great significance in improving the vaccination against plague. Analysis of the experimental data on the protection of Yersinia pestis showed that firstly the biopolymers on the surface of F_1 and the cells of the bacterial cells showed relatively high immunogenicity. Experiments show that they are a variety of experimental animals are protective. Protective studies on other Yersinia pestis antigen preparations (ОСА, ЛПС, V, T, L, 4, etc.) were inadequate. However, there are also a few materials that can be envisaged to prevent the introduction of at least some of these antigens in plague immunity