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原发性手汗症(primary hyperhidrosis,PH)是指手部汗腺分泌异常亢进,与外界环境温度高低无关,发病机制较复杂,尚未完全掌握.目前治疗方式主要以切断上胸段交感神经链中的节间束纤维为主.本文主要针对原发性手汗症发病机制、症状、治疗机制及多种微创手术治疗方法等内容作一综述,提出胸腔镜下胸交感神经链切断术是治疗原发性手汗症最常用、最有效的微创方法.“,”To discuss the pathogenesis, symptom and therapeutic mechanism of primary hyperhidrosis, we found that endoscopic thoracic sympathectomy is the most commom and effective minimally invasive treatment for primary hyperhidrosis.Compensatory hyperhidrosis was the most common complication in post-operation, reserve the T2 could reduce the incidence.T3 and (or) T4 endoscopic thoracic sympathectomy will the best method to primary hyperhidrosis. One incision, single position and general anesthesia will the best operation scheme.