论文部分内容阅读
近年来,我们收治了7例肝硬化继发肾病综合征病人,年龄为36～60岁,肝硬化后出现肾病的时间为4.5±1.9年。7例病人均有颜面和下肢浮肿、腹水,少尿2例,上消化道出血1例。血浆蛋白为10～20g/L,24小时尿蛋白定量为3.6～8.9g/24h,均符合第二届全国肾脏病学术会议制订的肾病综合征的诊断标准。 1.治疗方法及疗效:除一般对症治疗外,均静滴环磷酰胺1mg/(kg.d),每日或隔日1次,1个月为1疗程,连用3～4个疗程。治疗期间定期查肝功、周围血象。
In recent years, we treated 7 patients with secondary cirrhosis with nephrotic syndrome, aged 36 to 60 years old, cirrhosis of the kidney after the time was 4.5 ± 1.9 years. Seven patients had facial and lower extremity edema, ascites, oliguria in 2 cases, 1 case of upper gastrointestinal bleeding. Plasma protein 10 ~ 20g / L, 24-hour urine protein was 3.6 ~ 8.9g / 24h, are in line with the Second National Nephrology Conference developed diagnostic criteria for nephrotic syndrome. 1. Treatment and efficacy: In addition to the general symptomatic treatment, intravenous cyclophosphamide 1mg / (kg.d), daily or every other day, 1 month for a course of treatment, once every 3 to 4 courses. Regular check liver function during treatment, peripheral blood.