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目的 观察应用亚低温技术治疗脑出血的临床疗效和对血浆内皮素的影响。方法 随机将 40例脑出血病人分为治疗组和对照组各 2 0例 ,治疗组在药物综合治疗基础上加用亚低温技术治疗 ,对照组为单纯药物综合治疗 ;治疗开始前及治疗后 2 8天分别进行神经功能缺损评分 ,并检测血浆内皮素的变化。结果 治疗 2 8天后 ,治疗组的神经功能缺损评分明显低于对照组 (P <0 0 1) ,血浆内皮素的浓度也明显低于对照组 (P <0 0 1)。病死率治疗组为 15 % ,对照组为 2 0 %。结论 亚低温技术可以明显改善脑出血患者的神经功能及预后
Objective To observe the clinical effect of using mild hypothermia on cerebral hemorrhage and its effect on plasma endothelin. Methods A total of 40 patients with intracerebral hemorrhage were randomly divided into treatment group and control group with 20 cases in each group. The treatment group was treated with mild hypothermia on the basis of comprehensive drug treatment, while the control group was treated with simple drug synthesis. Before treatment and 2 Eight days later, neurological deficit scores and plasma endothelin levels were measured. Results After 28 days of treatment, the score of neurological deficit in the treatment group was significantly lower than that of the control group (P <0.01), and the plasma endothelin concentration was also significantly lower than that of the control group (P <0.01). The case fatality rate was 15% in the treatment group and 20% in the control group. Conclusion Mild hypothermia can significantly improve the neurological function and prognosis of patients with intracerebral hemorrhage