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目的探讨不同的联合用药方案预防治疗高危产妇产后出血疗效,寻求对产后出血较好预防治疗方法。方法总结分析2009年1月至2011年12月于广东省高要市人民医院住院行剖宫产术有产后出血高危因素的产妇165例,根据不同的治疗方法分为观察组(A组)85例,胎儿娩出后即于子宫壁肌层内注射缩宫素20 IU加卡前列素氨丁三醇250μg。对照组(B组)80例,胎儿娩出后即于子宫壁肌层内注射缩宫素20 IU,术毕予米索前列醇600μg纳肛。比较两组术中出血量,术后24 h出血量,及其产生的不良反应,产后出血发生率。结果剖宫产术中、产后24 h的出血量及其产生的不良反应A组明显少于B组(P<0.05)。结论剖宫产术中胎儿娩出后即于子宫壁肌层内注射缩宫素加卡前列素氨丁三醇预防高危产妇产后出血优于缩宫素加米索前列醇方案,且用药安全、副反应小,为预防高危产妇产后出血较好预防治疗方案。
Objective To explore different combinations of drug prevention and treatment of high-risk maternal postpartum hemorrhage efficacy, to seek better prevention and treatment of postpartum hemorrhage. Methods A total of 165 maternal women with cesarean section who were at risk of postpartum hemorrhage were admitted to Gaoyao People ’s Hospital of Guangdong Province from January 2009 to December 2011. According to different treatment methods, they were divided into observation group (group A) 85 For example, after delivery of the fetus in the uterine parietal muscle injection of oxytocin 20 IU plus carboplatin Tromethamine 250μg. The control group (B group) 80 cases, the fetus after delivery in the uterine wall muscle injection of oxytocin 20 IU, the completion of surgery to misoprostol 600 μg anal rectal. The amount of bleeding during operation, the amount of bleeding at 24 hours after operation, and the adverse reactions and the incidence of postpartum hemorrhage were compared between the two groups. Results In cesarean section, the amount of hemorrhage and the side effects of 24 h postpartum were significantly less in group A than in group B (P <0.05). Conclusion Intrauterine injection of oxytocin and metacoprost trometamol in cesarean section after fetus is delivered is superior to oxytocin plus misoprostol in preventing postpartum hemorrhage in high-risk maternal women. Small reaction, to prevent high-risk maternal postpartum hemorrhage better prevention and treatment programs.