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OBJECTIVE: The purpose of the study was to characterize the perinatal outcom e of pregnancies complicated by placenta accreta. METHODS: We conducted a case-co ntrol analysis of all deliveries between the years 1990 and 2000 that were compl icated by placenta accreta. Perinatal variables included in the analysis were ge stational age at delivery, birth weight, Apgar scores, and perinatal mortality. Statistical analysis was performed using both the unpaired and paired approach. P < .05 was considered significant. RESULTS: The study encompassed 34,450 delive ries, from which 310 cases of placenta accreta were diagnosed (0.9%) and compar ed with 310 matched controls. In the pregnancies complicated by placenta accreta , we found a statistically significant increase in preteral deliveries (10.7%ve rsus 1%, P < .001, odds ratio 12.1, 95%confidence interval 3.7-39.9) and smal l-for-gestational-age babies (27.3%versus 14%, P < .001, odds ratio 5.05, 9 5%confidence interval 1.46-3.28). CONCLUSION: Pregnancies complicated by place nta accreta are at increased risk for perinatal adverse outcome. We speculate th at these findings may arise from pathological implantation of the placenta, resu lting in interference with normal fetal growth.
OBJECTIVE: The purpose of the study was to characterize the perinatal outcom e of pregnancies complicated by placenta accreta. METHODS: We conducted a case-co ntrol analysis of all deliveries between the years 1990 and 2000 that were compl icated by placenta accreta. Perinatal variables included in the analysis were ge stational age at delivery, birth weight, Apgar scores, and perinatal mortality. P <.05 was considered significant. RESULTS: The study encompassed 34,450 delive ries, From the 310 cases of placenta accreta were diagnosed (0.9%) and compar ed with 310 matched controls. In the pregnancies complicated by placenta accreta, we found a statistically significant increase in preteral deliveries (10.7% ve rsus 1%, P <.001 , odds ratio 12.1, 95% confidence interval 3.7-39.9) and smal l-for-gestational-age babies (27.3% versus 14%, P <0.001, odds ratio 5.05, 95% confidence interval 1.46-3.28) CONCLUSIO N: Pregnancies complicated by place nta accreta are at increased risk for perinatal adverse outcome. We speculate th at these findings may arise from pathological implantation of the placenta, resu lting in interference with normal fetal growth.