原发于肝的恶性纤维组织细胞瘤极少见,现将遇到一例报道如下: 患者男性,60岁。因右上腹部胀痛一周而入院。无发热,呕吐及黄疸。体检:肝上界第6肋间,下界不清,肝区叩痛明显。锁骨上淋巴结(一)。肝功能正常,AFP(一)。B超及肝动脉造影均提示右肝占位性病变。术中见肝右后叶有巨大肿块,质硬,已向横膈侵犯并有粘连。临床诊断为肝癌。病理检查:右肝叶组织,表面高低不平,肿块大小13×9×9cm,切面淡黄色,有假包膜。瘤体近边缘部分呈细编织状,质地较韧,中心部分质较软,有坏死。镜下:瘤组织主要由异型肥胖纤维母细胞和组织细胞所构 Primary malignant fibrous histiocytoma of the liver is rare, and one case will be reported as follows: The patient is male, 60 years old. The hospital was admitted to hospital because of a week of pain in the right upper abdomen. No fever, vomiting and jaundice. Physical examination: the 6th intercostal space in the upper liver, the lower border is unclear, and the pain in the liver area is obvious. Supraclavicular lymph nodes (1). Normal liver function, AFP (a). B-ultrasound and hepatic arteriography showed right hepatic space-occupying lesions. During the operation, there was a huge mass in the right posterior lobe of the liver, which was hard and had been violated and adhered to the diaphragm. Clinical diagnosis is liver cancer. Pathological examination: right liver lobe, uneven surface, mass size 13 × 9 × 9cm, cut surface light yellow, pseudocapsule. The proximal part of the tumor was finely woven, and the texture was relatively tough. The central part was soft and necrotic. Microscopically: Tumor tissue is mainly composed of abnormally-shaped obese fibroblasts and histiocytes.