胰腺神经内分泌肿瘤(pNET)是一种少见疾病,根据是否伴随相应的内分泌症状分为功能性和无功能性两类。手术是pNET最主要的治疗手段,近年来随着对pNET发病机制的了解,新的诊断技术和治疗手段的出现,以及多学科协作诊治模式的应用,pNET的诊断和治疗发生了巨大的变化,为pNET患者尤其是晚期患者带来了希望。 Pancreatic neuroendocrine tumors (pNET) is a rare disease that is classified into functional and non-functional categories depending on whether or not the corresponding endocrine symptoms are present. Surgery is the most important treatment for pNET. In recent years, with the understanding of the pathogenesis of pNET, the emergence of new diagnostic techniques and treatments, and the application of multidisciplinary collaborative diagnosis and treatment modes, the diagnosis and treatment of pNET have undergone tremendous changes. Hope for pNET patients, especially for advanced patients.