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目的将妊娠期高血压疾病(HDPs)孕妇孕中期母体体成分以及妊娠结局与正常孕妇比较,分析之间的异同。方法选择在我院建卡并在我院分娩的妊娠期高血压疾病的单胎孕妇74例,其中妊娠高血压25例,轻度子痫前期37例,重度子痫12例,选取同时期在我院建卡、足月分娩的单胎健康孕妇148例,回顾性分析这些孕妇在孕中期20-28周人体成分的异同。结果 HDPs组孕妇孕前体重、BMI均高于正常组;孕中期母体成分方面,细胞内外液、水分含量、蛋白质、矿物质、骨骼肌肉量、去脂体重、脂肪、内脏脂肪HDPs组均高于正常组(P<0.05),HDPs组内各亚组间体成分无明显差异(P≥0.05)。结论妊娠期高血压疾病孕妇孕中期体成分,尤其是水分和脂肪显现出与正常孕妇明显的差异,与HDPs疾病的特点及病理生理机制相符。
OBJECTIVE: To compare the similarities and differences between maternal components of pregnant women with gestational hypertension (HDPs) during the second trimester of pregnancy and pregnancy outcomes and normal pregnant women. Methods Totally 74 pregnant women with singleton pregnancies were enrolled in this study. Among them, there were 74 cases of singleton pregnancies with gestational hypertension, including 25 cases of pregnancy-induced hypertension, 37 cases of mild preeclampsia and 12 cases of severe eclampsia. Our hospital built card, full-term childbirth of singleton healthy pregnant women in 148 cases, a retrospective analysis of these pregnant women in the second trimester of 20-28 weeks human body composition similarities and differences. Results The body weight and BMI of pregnant women in HDPs group were significantly higher than those in normal pregnant women. In the second trimester of pregnancy, the levels of cellular extracellular fluid, water content, protein, minerals, skeletal muscle mass, lean body fat, fat, (P <0.05). There was no significant difference in body composition among all subgroups in HDPs group (P> 0.05). Conclusions Pregnant women with gestational hypertension have significantly different body composition, especially moisture and fat, from their normal counterparts in the second trimester of pregnancy, and are consistent with the characteristics of HDPs and their pathophysiological mechanisms.