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目的:研究腹泻型、便秘型肠易激综合征(IBS)和功能性便秘患者直肠感觉阈的变化,以及性别和年龄对直肠感觉阈的影响.方法:腹泻型IBS(n=18)、便秘型IBS(n=14)、功能性便秘(n=30)和健康对照组(n=18),通过直肠充气扩张评价直肠感觉阈的变化.结果:⑴腹泻型IBS直肠第一感觉阈、排便阈和痛阈均显著低于便秘型IBS、功能性便秘以及健康对照组(P<0.01);⑵便秘型IBS、功能性便秘和健康对照组三组患者的直肠感觉阈值,两两比较均无显著性差异(P>0.1);⑶腹泻型IBS、便秘型IBS、功能性便秘以及健康对照组各组女性的直肠感觉阈值均低于男性(P<0.05);⑷各组20-50岁人群和50-80岁人群的直肠感觉阈值无显著性差异(P>0.05).结论:腹泻型IBS患者直肠感觉阈显著低于便秘型IBS、功能性便秘以及健康对照组;而便秘型IBS、功能性便秘和健康对照组之间的直肠感觉阈无显著差异.男性的直肠感觉阈值高于女性.年龄对直肠感觉阈值无明显影响.
Objective: To study the changes of rectal sensation threshold in diarrhea-predominant constipation-predominant irritable bowel syndrome (IBS) and functional constipation patients and the effect of gender and age on rectal sensory threshold.Methods: Diarrhea-predominant IBS (n = 18) (N = 14), functional constipation (n = 30), and healthy control group (n = 18) .The rectal inflation threshold was used to evaluate the rectal sensation threshold.Results: Threshold and pain threshold were significantly lower than constipation IBS, functional constipation and healthy control group (P <0.01); ⑵ constipation IBS, functional constipation and healthy control group three patients rectal sensory threshold, no comparison of any two (P> 0.05); (3) The rectal sensation thresholds of diarrhea IBS, constipation IBS, functional constipation and healthy control group were lower than those of male (P <0.05); (4) (P> 0.05) .Conclusion: The rectal sensory threshold in IBS patients with diarrhea is significantly lower than that of constipation IBS, functional constipation and healthy control group, while constipation IBS, function There was no significant difference in sensory rectal sensation between constipation and healthy controls. Threshold was higher than that of females.Ages had no significant effect on rectal sensation threshold.