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柳毒蛾核型多角体病毒（ＳｓＮＰＶ）杀虫剂对柳毒蛾幼虫有较强的致病力。安全性实验结果表明：牛经口１次平均灌入３８×１０１１ＰｉＢ／头，绵羊１２×１０１１ＰｉＢ／只，牛、羊、兔经皮多次涂抹，小鼠、兔、鸽分别经口、鼻、静脉、皮下注射等途径接毒均未引起异常表现。各项生理指标与对照组比无显著性差异。脏器剖检未见病理致变及ＳｓＮＰＶ侵染。小鼠生殖毒性实验其受胎率正常，未引起畸胎及脏器畸变。经对某些昆虫及鸡胚单层细胞接毒浸染，证明ＳｓＮＰＶ不能在非宿主细胞体内存活扩繁。
The virulent virulent virulent nucleocapsid nuclear polyhedrosis virus (SsNPV) has strong virulence to larvae of the larva. The results of safety experiment showed that: 1, 2 × 1011PiB / head, 1 × 2 × 1011PiB / Oral, nasal, intravenous, subcutaneous injections and other routes of poisoning did not cause abnormal performance. The physiological indicators and the control group no significant difference. There was no pathological change and SsNPV infection in organs. The mice reproductive toxicity test normal rate of conception, did not cause teratogenic and organ distortion. The infection of some insects and chick embryo monolayers proved that SsNPV could not survive in the non-host cells.