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文献报告干扰素有抗肿瘤和使喉乳头状瘤消退的作用。本文报告一个用干扰素治疗喉乳头状瘤的同时并发鳞状细胞癌的病例。病人是一个出生于1964年的男孩。在一岁前即确诊患幼年性喉乳头状瘤。由于呼吸道阻塞,需要行气管切开术。此后、病人一直带气管套管。虽多次经内窥镜手术摘除、冷冻和显微镜下烧灼、乳头状瘤继续向气管及左支气管蔓延。1974年用自体免疫及博来霉素治疗.仅暂时有效;1978～1979年用左唑咪治疗则没有任何效果。以后遂开始用人干扰素β肌注,每月做内窥镜检查,证明气管、支气管乳头状瘤消退,只是在停药时,乳头状瘤又复发。三个月后,又用人干扰素α肌注,持续4(1/2)月,
Interferon has been reported in the literature as anti-tumor and regression of laryngeal papilloma. This article reports a concurrent case of squamous cell carcinoma treated with interferon for laryngeal papilloma. The patient is a boy born in 1964. A year before the diagnosis of juvenile laryngeal papilloma. Tracheotomy is required because of obstructive airway obstruction. Since then, patients have been tracheal tube. Although many endoscopic surgery removed, frozen and under the microscope burning, papilloma continue to the trachea and left bronchus. 1974 with autoimmune and bleomycin treatment only temporarily effective; 1978 ~ 1979 with leflunomide treatment had no effect. Later began to use human interferon β intramuscular injection, endoscopy every month to prove that the trachea, bronchial papilloma regression, only in withdrawal, papilloma recurrence. Three months later, human interferon alpha was injected intramuscularly for 4 (1/2) months,