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应用间接荧光抗体试验对江苏省两个采取不同抗疟措施地区的人群在1982年间进行了连续4次的纵向观察。单纯采取现症病人治疗措施的对照组178例,治疗病人加上室内滞留喷洒与孳生地灭蚊的灭蚊组182例。在措施期间的3、6、8及10月各调查1次。结果,两组的抗体阳性率与几何平均倒数滴度均随年龄增长而升高,3月份两组抗体阳性率差异不显著,在其他三次调查中,灭蚊组均低于对照组,4~15岁年龄组尤明显。提示药物治疗加灭蚊对控制疟疾的效果较好。间接荧光抗体试验的结果与疟原虫调查及随访结果相符,而低年龄组的血清学资料较易反映这一变化。同时证明间接荧光抗体试验可用于评价抗疟措施的效果。
Indirect Fluorescent Antibody Tests Four consecutive longitudinal studies were conducted in 1982 in two populations in Jiangsu Province who took different antimalarial measures. 178 patients in the control group who were treated with the present disease were treated with anti-mosquito alone in 182 cases. The surveys were conducted in March, June, August and October during the survey period. The results showed that the antibody positive rate and reciprocal geometric mean reciprocal titer increased with age in both groups. There was no significant difference in antibody positive rate between the two groups in March. In the other three surveys, the mosquito control group was lower than the control group, The 15-year-old group is especially noticeable. Tip drug treatment plus mosquito control of malaria better. Indirect fluorescent antibody test results and the results of the survey and follow-up of malaria parasites consistent with the serological data of younger age groups more easily reflect this change. Indirect fluorescent antibody tests have also been demonstrated to evaluate the effectiveness of antimalarial measures.