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运用药理生理学的方法，观察温胆降脂口服液对高脂血成年ＳＤ大鼠血清三酰甘油、血清胆固醇、腹腔脂肪积累、体重增长的影响，并与绞股蓝总甙进行比较。用药２１ｄ，温胆降脂口服液组大鼠体重明显低于绞股蓝总甙组（Ｐ＜０．０５）；温胆降脂口服液组的腹腔脂肪含量明显少于绞股蓝总甙组；温胆降脂口服液组与绞股蓝总甙组血清三酰甘油平均下降０．６０、０．４８ｍｍｏｌ／Ｌ；血清胆固醇平均下降０．４９、０．４０ｍｍｏｌ／Ｌ，两组动物的血清三酰甘油和血清胆固醇，用药后均有显著降低（Ｐ＜０．０５），温胆降脂口服液的效果明显优于绞股蓝总甙。结果表明，温胆降脂口服液对降低高胆固醇和高脂肪摄入后血清三酰甘油、血清胆固醇的含量，减少腹腔脂肪的积累，控制成年大鼠的体重增长具有明显的作用，其疗效优于对照组药物。
The effect of Wendan Jiangzhi Oral Liquid on serum triglyceride, serum cholesterol, abdominal fat accumulation and body weight gain of hyperlipidemia adult SD rats was observed by pharmacological physiology and compared with that of Gynostemma pentaphyllum. After 21 days of medication, the body weight of Wendan Jiangzhi Oral Liquid group was significantly lower than that of Gynostemma Pentaphyllum group (P<0.05). The abdominal fat content of Wendan Jiangzhi Oral Liquid group was significantly lower than that of Gynostemma Pentaphyllum group; The serum triacylglycerol levels in the lipid oral solution group and the Gynostemma quinone group decreased by an average of 0.60 and 0.48 mmol/L, and the serum cholesterol levels decreased by an average of 0.49 and 0.40 mmol/L. Serum triacylglycerols and serum cholesterol levels in the two groups of animals After treatment, there was a significant decrease (P<0.05). The effect of Wendan Jiangzhi Oral Liquid was significantly better than that of Gynostemma pentaphyllum. The results showed that Wendan Jiangzhi Oral Liquid had a significant effect on decreasing the serum triglyceride and serum cholesterol levels, reducing the accumulation of abdominal fat, and controlling the body weight gain of adult rats after high cholesterol and high fat intake. In the control group drugs.