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目的探讨小剂量氯胺酮复合异丙酚静脉麻醉在经十二指肠胆道检查治疗术中的安全性与可行性。方法将60例患者随机均分成两组。麻醉组在异丙酚和氯胺酮复合麻醉下进行检查和治疗;对照组术前肌肉注射哌替啶50mg和地西泮10mg。观察比较两组患者的呼吸循环指标、操作过程评分和镇静评分。结果麻醉组操作评分和镇静评分明显优于对照组。两组术前循环指标无统计学差异,麻醉组术中循环指标与术前比较无统计学差异,但显著性低于常规组的相同时间点(P<0.05);常规组术中循环指标显著性高于其术前(P<0.05)。结论小剂量氯胺酮复合异丙酚的麻醉方法应用于经十二指肠胆道检查治疗术是安全可行的,并且该方法对循环指标不稳定和依从性差的患者具有优越性。
Objective To investigate the safety and feasibility of low dose ketamine combined propofol intravenous anesthesia in the treatment of duodenal biliary tract. Methods Sixty patients were randomly divided into two groups. The anesthesia group was examined and treated under propofol and ketamine combined anesthesia. The control group was intramuscularly injected with pethidine 50 mg and diazepam 10 mg. Respiratory cycle index, operation procedure score and sedation score were observed and compared between the two groups. Results The operation score and sedation score of the anesthesia group were significantly better than those of the control group. There was no significant difference between the two groups in the preoperative circulation index, but there was no significant difference between the two groups (P <0.05). The circulatory index in the conventional group was significantly higher than that in the conventional group Sex than its preoperative (P <0.05). Conclusion It is safe and feasible to apply anesthesia with low-dose ketamine combined with propofol in the treatment of duodenal biliary tract. This method is superior to patients with unstable circulation index and poor compliance.