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目的:了解泌尿外科真菌感染的危险因素及病原菌分布特点,以制定和预防泌尿外科真菌感染的方案。方法:回顾性分析了我院泌尿外科2013年1月-2016年1月真菌感染和非真菌性感染的病例,其中真菌感染患者124例为观察组,非真菌性感染患者130例为对照组,并了解病原菌分布情况,找出泌尿外科真菌感染的各种危险因素。结果:观察组使用抗菌药物天数(29.72±22.52)d,三线用药使用率52.42%,基础疾病发生率70.97%,导管留置率81.45%,≥60岁患者占69.35%;对照组使用抗菌药物天数(19.53±17.54)d,三线用药使用率14.61%,基础疾病发生率41.54%,导管留置率56.15%,≥60岁患者占48.46%,以上差异均有统计学意义(P<0.05)。观察组最常见病原菌为念珠菌,占84.00%。结论:长期使用高级别抗菌药物、基础疾病、导管留置、高龄是引起泌尿外科真菌感染重要的危险因素,泌尿外科真菌感染最常见的病原菌是念珠菌。
Objective: To understand the risk factors of urological fungal infection and the distribution of pathogens in order to develop and prevent urological fungal infections program. Methods: A retrospective analysis of our hospital urology from January 2013 to January 2016 cases of fungal infections and non-fungal infections, including 124 cases of fungal infection in the observation group, 130 cases of non-fungal infection in the control group, And understand the distribution of pathogens to identify various risk factors for urological fungal infections. Results: In the observation group, the days of using antibacterials were 29.72 ± 22.52 d, the rates of three-line use were 52.42%, the incidences of underlying diseases were 70.97%, the catheterization rate was 81.45%, and those of patients ≥60 years old were 69.35% 19.53 ± 17.54) d, the rate of the third-line medication was 14.61%, the rate of the underlying diseases was 41.54%, the catheterization rate was 56.15%, and the rate of patients ≥60 years old was 48.46%, all of which were statistically significant (P <0.05). The most common pathogen in the observation group was Candida, accounting for 84.00%. Conclusion: Long-term use of high-level antimicrobial agents, underlying diseases, catheter indwelling, and advanced age are important risk factors for urological fungal infections. The most common pathogen of urological fungal infections is Candida.