论文部分内容阅读
目的：对新生牛促肝细胞生长因子（ Ｈ Ｇ Ｆ）的主要药效学进行研究。方法：采用存活率测定、 Ｓ Ｇ Ｐ Ｔ 活性测定、组织病理学观察、体内外３ Ｈ Ｔｄ Ｒ 掺入实验。结果： Ｈ Ｇ Ｆ 能够降低急性肝损伤小鼠的存活率及 Ｓ Ｇ Ｐ水平，能够促进损伤肝组织结构复原及肝细胞再生。结论：实验证明 Ｈ Ｇ Ｆ 具有十分理想的临床应用价值。
Objective: To study the main pharmacodynamics of neonatal bovine hepatocyte growth factor (H G F). Methods: Survival rate, S G P T activity assay, histopathological observation, 3 H Td R incorporation in vitro and in vivo were used. Results: HG F could reduce the survival rate and the level of S G P in acute liver injury mice, and promote the structural recovery of hepatic tissue and the regeneration of hepatocytes. Conclusion: It has been proved by experiments that H G F has very good clinical value.