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目的胃Dieulafoy病出血可使病人在短时间内进入休克状态而危及生命,曾是外科手术治疗的适应证。我科采用奥曲肽(善宁)联用奥美拉唑治疗胃Dieulafoy病出血12例,观察其疗效。方法常规给予输血、补充血容量、抗休克等综合治疗,同时应用止血剂、黏膜保护剂,静脉注射奥美拉唑40mg,2次/d,奥曲肽(善宁)25μg/h微泵入,连用3d。3d后根据病情逐步减量,共持续7d。结果所有病人均一次止血成功,时间3～6d,平均4.3d。结论观察显示,奥曲肽(善宁)联用奥美拉唑是内科保守治疗胃Dieulafoy病出血的有效方法,有助于达到止血和降低手术率的目的。
The purpose of Dieulafoy disease bleeding can make the patient enter the state of shock in a short time life-threatening, was a surgical indications for surgery. Our department used octreotide (Shanning) combined with omeprazole in the treatment of gastric Dieulafoy disease bleeding in 12 cases observed its efficacy. Methods The routine therapy was given blood transfusion, blood volume supplement, anti-shock and so on. At the same time hemostatic agent and mucosal protective agent were intravenously injected omeprazole 40mg, twice a day, octreotide 25μg / h micro pump, 3d. 3d gradually reduced according to the condition, a total of 7d. Results All patients had a successful hemostasis, the time 3 ~ 6d, an average of 4.3d. Conclusions The observation shows that octreotide combined with omeprazole is an effective method for the conservative treatment of gastric Dieulafoy’s disease in medical department, which helps to achieve hemostasis and reduce the operation rate.