视网膜母细胞瘤是一种幼儿视网膜肿瘤,其遗传病因学有两类:(1)常染色体显性遗传(外显率不全);(2)13q~-的人对视网膜母细胞瘤易感性高。新近关于13q~-病例的文献报道表明:缺失部位都在13q14区带。Yunis等应用早中期和晚前期显带技术,在一个患者中证明缺失亚带包括13q14.12,q14.13,q14.2,及部分13q14.11,q14.3。本文报告一例患者的细胞遗传学研 Retinoblastoma is an infantile retinal tumor. There are two types of hereditary etiology: (1) autosomal dominant inheritance (incompleteness); (2) high susceptibility to retinoblastoma in 13q- . Recent reports on 13q~-cases have shown that the missing sites are in the 13q14 zone. Yunis et al. used early-middle and late-stage banding techniques to demonstrate in one patient that the deletion subbands included 13q14.12, q14.13, q14.2, and portions 13q14.11, q14.3. This article reports a case of cytogenetics in patients