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[目的]探讨影响cN0甲状腺微小癌复发的相关因素。[方法]回顾性分析118例cN0甲状腺微小癌患者的临床资料,单因素和多因素分析影响cN0甲状腺微小癌复发的因素。[结果]10年无病生存率及总生存率分别90%及100%。单因素分析显示,年龄、甲状腺上极肿瘤、肿瘤甲状腺外侵犯、中央区淋巴结转移为影响cN0甲状腺微小乳头癌复发的因素(P<0.05)。多因素分析显示肿瘤甲状腺外侵犯、中央区淋巴结转移数≥3枚是影响肿瘤复发的独立危险因素(P<0.05)。[结论]肿瘤甲状腺外侵犯、中央区淋巴结转移数≥3枚是cN0甲状腺微小癌复发的主要影响因素。
[Objective] To investigate the related factors that affect the recurrence of cN0 thyroid microcarcinoma. [Methods] A retrospective analysis of 118 cases of cN0 thyroid microcarcinoma in patients with clinical data, univariate and multivariate analysis of cN0 recurrence of thyroid cancer factors. [Results] The 10-year disease-free survival rate and overall survival rate were 90% and 100% respectively. Univariate analysis showed that age, thyroid gland tumor, extranodal invasion of the tumor and central lymph node metastasis were the factors affecting the recurrence of cN0 thyroid papillary carcinoma (P <0.05). Multivariate analysis showed that extrathyroidal tumor invasion, central lymph node metastasis ≥ 3 pieces is an independent risk factor for tumor recurrence (P <0.05). [Conclusion] Thyroid extracancerous invasion of tumor, the central lymph node metastasis number ≥ 3 pieces is the main influencing factor of recurrent microcarcinoma of cN0.