许多动物实验及氟中毒人群的调查资料均表明,慢性氟中毒不仅对机体骨骼、牙齿及肝脏有毒性作用,而且对其它组织器官的毒性作用越来越引起人们的重视。本实验观察大鼠氟中毒后多种组织器官的病理改变。1 材料与方法1.1 动物分组 Wistar大鼠32只,体重50～60g,随机分为2组,雌雄各半。实验组(16只鼠)饮含100mg/L氟化钠水,对照组饮用自来水(含氟0.40mg/L)。两组同食常备饲料,自由饮食。实验第180d,股动脉放血处死 Many animal experiments and fluorosis data indicate that chronic fluorosis not only has toxic effects on bones, teeth and liver, but also causes more and more toxicity to other tissues and organs. The experimental observation of fluorosis in rats after a variety of histopathological changes. 1 Materials and Methods 1.1 Animal Wistar 32 rats, weighing 50 ~ 60g, were randomly divided into two groups, male and female. Experimental group (16 rats) drinking 100mg / L sodium fluoride water, the control group drinking tap water (fluoride 0.40mg / L). Two groups with the same feed, free diet. On the 180th day, the femoral artery was exsanguinated