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老年人随年龄增长患病率增加,其中约80％的患病老人需要药物治疗。老年人用药不同于成年人,更有别于儿童。老年人常因各种生理功能退变和多脏器疾患,体内的药物吸收、分布、代谢、排泄和耐受等都有量和质的变化,个体差异也较成年人为大,用药剂量至今缺乏统一准则,有时常规剂量也引起严重毒副反应。有人统计老年人对药物的毒副反应为青年人的2.5～3倍。
The prevalence of the elderly increases with age, of which about 80% of the sick elderly need medication. Elderly medication is different from adults, more different from children. The elderly often due to a variety of physiological function degeneration and multiple organ diseases, the body of drug absorption, distribution, metabolism, excretion and tolerance are quantitative and qualitative changes, individual differences are also larger than adults, the dosage has been lacking Uniform guidelines, and sometimes conventional doses also cause serious side effects. Some statistics of the elderly toxic side effects of drugs for young people 2.5 to 3 times.