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目的探讨硝夫太尔制霉素阴道软胶囊治疗细菌性阴道病的临床效果。方法将2009年11月~2010年4月收治的117例细菌性阴道病患者遵照知情同意原则随机分为两组,对照组55例采用双唑泰栓治疗,观察组62例采用硝夫太尔制霉素阴道软胶囊治疗,对两组的治疗效果进行比较分析。结果两组患者总有效率间差异有统计学意义(P<0.05),且两组治疗过程中均未见影响治疗的严重不良反应发生。随访9个月,观察组、对照组的复发率分别为8.1%、10.9%,前者略低于后者,组间差异无统计学意义(P>0.05)。结论硝夫太尔制霉素阴道软胶囊治疗细菌性阴道病安全、有效,是临床的首选药物之一,值得关注。
Objective To investigate the clinical effect of nitrofurantoin vaginal soft capsule in the treatment of bacterial vaginosis. Methods A total of 117 bacterial vaginosis patients who were treated from November 2009 to April 2010 were randomly divided into two groups according to the principle of informed consent. The control group, 55 cases were treated with metoprolol, 62 cases of observation group were treated with nitrofutyl Nystagmus vaginal soft capsule treatment, the comparative analysis of the two groups of treatment. Results There was significant difference between the two groups in the total effective rate (P <0.05). No serious adverse reactions occurred in the two groups during treatment. The follow-up of 9 months showed that the recurrence rates of the observation group and the control group were 8.1% and 10.9% respectively, the former slightly lower than the latter, with no significant difference between the two groups (P> 0.05). Conclusions Nitrofurantone neomycin vaginal soft capsule is safe and effective in the treatment of bacterial vaginosis and is one of the most preferred drugs in clinical practice.