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目的 :评价长期配戴角膜接触镜对角膜内皮细胞的影响。方法 :将配戴角膜接触镜超过 5年以上的患者根据不同的戴镜种类分成四组 ,每组又以年龄划分为亚组 ( 2 0～ 6 0岁 ,每十岁一组 ) ,与相应年龄段的无戴镜史的人群比较。使用 Konan SP- 80 0 0角膜内皮细胞显微镜测量和计算角膜内皮细胞密度 ( CD) ,角膜内皮细胞面积变异系数 ( CV)和六角形细胞频率 ( 6 A( % ) )。结果 :PMMA镜片、低含水量软性镜片和低 Dk值 RGP镜片对角膜内皮细胞均有副作用 ,尤其对于年轻的配戴者 ,低 Dk值 RGP的影响要小于前两者。高Dk值 RGP镜片对角膜内皮细胞没有显著影响。结论 :为保证角膜内皮细胞的健康 ,角膜接触镜配戴者应该选择透氧性高的镜片
Objective: To evaluate the effect of long-term wearing contact lenses on corneal endothelial cells. Methods: Patients wearing contact lenses for more than 5 years were divided into four groups according to different types of wearing glasses. Each group was divided into subgroups (20 to 60, every 10 years) by age, Age group without the history of wearing glasses compared. Corneal endothelial cell density (CD), corneal endothelial area coefficient of variation (CV), and hexagonal cell frequency (6 A (%)) were measured and calculated using a Konan SP-80 0 corneal endothelial cell microscope. Results: PMMA lenses, low water content soft lenses and low Dk RGP lenses all had side effects on corneal endothelial cells. Especially for young wearers, the effect of low Dk RGP was less than that of the former two. High Dk values of RGP lenses did not have a significant effect on corneal endothelial cells. Conclusion: To ensure the health of corneal endothelial cells, contact lens wearers should choose lenses with high oxygen permeability