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体外实验证明热疗联合丝裂霉素(MMC)化疗对人结直肠癌细胞有明显的杀伤作用,但高温加上高浓度的MMC对正常组织器官势必有一定损害。我们于1997年6月至1998年6月对实验犬进行了MMC腹腔热灌注化疗,目的在于研究MMC腹腔热灌注化疗时的动物生命体征变化以及对实验动物
In vitro experiments show that hyperthermia combined with mitomycin (MMC) chemotherapy has a significant killing effect on human colorectal cancer cells, but high temperature and high concentration of MMC are bound to have some damage to normal tissues and organs. We carried out intraperitoneal hot perfusion chemotherapy on experimental dogs from June 1997 to June 1998. The purpose of this study was to investigate the changes of animal vital signs during the intraperitoneal hyperthermic perfusion chemotherapy of MMC and the effect on experimental animals