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山绿茶为广西少数民族民间中草药,具有活血通脉等治疗心血管疾病的功效。为观察山绿茶提取物对花生四烯酸钠盐(AA)、二磷酸腺苷(ADP)、盐酸肾上腺素(ADR)诱导的体外人血小板聚集的影响,通过阿司匹林为阳性药建立体外抗人血小板聚集模型,以健康人富血小板血浆为研究对象,分别以AA、ADP、ADR作为诱导剂,运用Born氏比浊法测定体外诱导的人血小板聚集率,探究不同山绿茶提取物对体外诱导的人抗血小板聚集的影响。实验结果表明:阳性药阿司匹林对诱导的体外人血小板聚集有明显抑制作用,而山绿茶各提取物对诱导的体外人血小板聚集无显著影响,虽然山绿茶提取物对体外人血小板聚集的抑制作用为阴性结果,但为地方中药材标准的完善提供了实验依据。
Mountain green tea for minority folk medicine in Guangxi, with blood circulation and other treatment of cardiovascular disease efficacy. In order to observe the effect of the extract of Sancha green tea on human platelet aggregation induced by arachidonic acid sodium salt (ADP) and adrenaline hydrochloride (ADR) in vitro, aspirin is used as positive drug to establish anti-human platelet in vitro Aggregation model of platelet-rich plasma in healthy volunteers were studied. AA, ADP and ADR were used as inducers respectively. Bone turbidimetry was used to determine the rate of human platelet aggregation in vitro, and the effects of different mountain green tea extracts on in vitro induced human Anti-platelet aggregation effect. The experimental results show that the positive drug aspirin can significantly inhibit the induced human platelet aggregation in vitro, while the extracts of the mountain green tea have no significant effect on the induction of human platelet aggregation in vitro. Although the inhibitory effect of the mountain green tea extract on human platelet aggregation in vitro is Negative results, but provided an experimental basis for the improvement of local Chinese herbal medicine standards.