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目的：观察胃粘膜保护剂替普瑞酮、麦滋林对胃粘膜幽门螺杆菌（Hp）感染和粘膜防御能力的作用。方法：用比色的方法测胃粘膜氨基已糖含量，用W－S银染色法检查Hp，观察1993年～1994年中收治的慢性浅表性胃炎患者。结果：替普瑞酮增加Hp阴性（18±5）mg／g和阳性（16±4）mg／g病人的胃粘膜氨基已糖含量；安滋林组治疗前后氨基已糖无明显增加。替普瑞酮、麦滋林抑制Hp，有效抑制率分别为76．92％和77．78％，两者无显著差异（P＜0．05）。结论：替普瑞酮和安滋林抑制Hp的生长，这种抑制作用似乎和氨基已糖的增加关系不十分密切。
Objective: To observe the effect of gastric mucosal protective agent teprenone and mazlin on gastric mucosal Helicobacter pylori (Hp) infection and mucosal defense. Methods: Gastric mucosal aminohexose content was measured by colorimetric method. Hp was detected by W-S silver staining. The patients with chronic superficial gastritis admitted from 1993 to 1994 were observed. Results: Teprenone increased the content of aminohexose in gastric mucosa in Hp negative (18 ± 5) mg / g and positive (16 ± 4) mg / g patients, while the Aminzamide group had no significant increase before and after treatment. Teprenone, MaiZhiLin inhibit Hp, the effective inhibition rates were 76.92% and 77.78%, no significant difference between the two (P <0.05). CONCLUSIONS: Teprenone and Arzolin inhibit the growth of Hp, and this inhibitory effect appears to be less closely related to the increase in hexose aminoglycoside.