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星形细胞上调基因-1(AEG-1)是一种原癌基因,多项研究均表明该基因在多种恶性肿瘤的发生、发展过程中起着重要作用,能够促进癌症的发生与发展,同时,该基因逐渐成为多种肿瘤临床诊断和预测预后的关键因子。本文就AEG-1基因在肿瘤中的作用机制以及近年来的研究进展做一简要介绍。
Astrocytic up-regulation gene-1 (AEG-1) is a protooncogene. A number of studies have shown that this gene plays an important role in the occurrence and development of many malignant tumors and can promote the occurrence and development of cancer. At the same time, the gene has gradually become the key factor in clinical diagnosis and prognosis of many tumors. In this paper, the mechanism of AEG-1 gene in tumor and the research progress in recent years to make a brief introduction.